Description
FOX04-DRI (Forkhead box O4 – D-Retro-Inverso peptide) is a synthetic peptide studied primarily for its potential role in targeting and clearing senescent (aging) cells, making it a focus in cellular senescence research.
Purpose and Mechanism:
FOX04-DRI functions as a senolytic agent. It achieves this by selectively disrupting the interaction between the FOXO4 transcription factor and $text{p}53$ within senescent cells. This disruption interferes with the survival pathways that aging cells use to avoid apoptosis (programmed cell death). By inducing apoptosis only in the dysfunctional senescent cells, FOX04-DRI aims to reduce the burden of these cells on tissues.
Product Specification:
This product is supplied as 10mg of high-purity FOX04-DRI.
Note: This product is sold strictly for research purposes only.




