Cellular & Metabolic Compounds
5-Amino-1MQ
10mgC₁₀H₁₁N₂⁺
Key Research Findings
- Neelakantan et al. — identification and characterisation of 5-Amino-1MQ as a selective small-molecule NNMT inhibitor.
- Published cell-culture studies on NNMT inhibition and associated NAD⁺ / SAM modulation.
- Animal-model studies on white-adipose-tissue metabolism under NNMT-inhibition conditions.
Overview
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). Supplied as a lyophilised powder for in-vitro research use only.
Mechanism of Action
Reported in published in-vitro and animal-model studies to competitively inhibit NNMT, the enzyme that methylates nicotinamide. Lowered NNMT activity is reported in cell-culture assays to raise intracellular NAD⁺ and S-adenosylmethionine (SAM) levels. Not intended for human or veterinary use.
Research Effects
NNMT Inhibition Assays
Moderate ResearchReported in cell-culture assays as a competitive inhibitor of nicotinamide N-methyltransferase.
NAD⁺ / SAM Modulation Studies
Preliminary ResearchEarly-stage in-vitro data on intracellular NAD⁺ and S-adenosylmethionine levels under NNMT inhibition.
Adipose-Metabolism Models
Preliminary ResearchAnimal-model studies on white-adipose-tissue metabolism and body-composition endpoints.
Laboratory Research Only — All information on this page is provided for scientific research purposes only. This is a certified reference material sample sold and distributed for laboratory research only.
Quick Facts
Research Status Key
Related Peptides
Cellular & Metabolic Compounds
NAD+
NAD+ is nicotinamide adenine dinucleotide, a redox coenzyme present in every living cell and one of the most studied molecules in biochemistry. It is not a peptide, and we group it under cellular and metabolic compounds for that reason. It cycles between an oxidised form, NAD+, and a reduced form, NADH, carrying electrons between the reactions of glycolysis, the citric acid cycle and oxidative phosphorylation. Beyond that classical role it is consumed as a substrate by three families of enzymes, which is what has driven the recent research interest. We supply it as a powder at 500mg per vial with an independent certificate of analysis.
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Cellular & Metabolic Compounds
MOTS-C
MOTS-c is a 16 amino acid peptide encoded not in nuclear DNA but within the mitochondrial 12S ribosomal RNA gene, making it one of a small group of mitochondrial-derived peptides identified since 2015. Its discovery is relatively recent, so the literature is smaller than for the older research peptides in this catalogue, but it is growing quickly and comes from mainstream metabolic research groups rather than from a single laboratory. We supply it as a lyophilised powder at 10mg per vial with an independent batch certificate of analysis reporting HPLC purity and mass spectrometry identity.
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Cellular & Metabolic Compounds
Cagrilintide
Cagrilintide is a long-acting synthetic amylin analogue. Supplied as a lyophilised powder for in-vitro research use only.
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