Synthetic Peptide Analogues
Epitalon
10mgC₁₄H₂₂N₄O₉
Key Research Findings
- Khavinson et al. — characterisation of the tetrapeptide sequence and telomerase-transcription assays.
- Published cell-culture data on TERT gene expression.
- In-vitro pineal cell-line studies on melatonin-pathway enzymes.
Overview
Epitalon (Epithalon) is a synthetic tetrapeptide derived from a sequence identified in pineal-gland extracts. Supplied as a lyophilised powder for in-vitro research use only.
Mechanism of Action
Reported in published in-vitro studies to modulate telomerase (TERT) transcription in somatic cell-culture assays. Not intended for human or veterinary use.
Research Effects
TERT Transcription Studies
Moderate ResearchReported in cell-culture studies as a modulator of telomerase reverse-transcriptase transcription.
Telomere-Length Assays
Moderate ResearchPublished in-vitro studies report measurable changes in telomere length in cultured somatic cells.
Pineal Enzyme Studies
Preliminary ResearchEarly-stage pineal cell-line studies on melatonin-pathway enzyme activity.
References
- [1]Araj SK, Brzezinski K, Szeleszczuk L. Overview of Epitalon: Highly Bioactive Pineal Tetrapeptide with Promising Properties. Int J Mol Sci. 2025. PMID 40141333 · doi:10.3390/ijms26062691
Cited for the molecular pathways described above. Listing a study is not a claim about any outcome in humans.
Laboratory Research Only — All information on this page is provided for scientific research purposes only. This is a certified reference material sample sold and distributed for laboratory research only.
Quick Facts
Research Status Key
Featured in Bundles
Epitalon is included in the following Zenterex research peptide bundles.
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Cellular & Metabolic Compounds
NAD+
NAD+ is nicotinamide adenine dinucleotide, a redox coenzyme present in every living cell and one of the most studied molecules in biochemistry. It is not a peptide, and we group it under cellular and metabolic compounds for that reason. It cycles between an oxidised form, NAD+, and a reduced form, NADH, carrying electrons between the reactions of glycolysis, the citric acid cycle and oxidative phosphorylation. Beyond that classical role it is consumed as a substrate by three families of enzymes, which is what has driven the recent research interest. We supply it as a powder at 500mg per vial with an independent certificate of analysis.
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Cytoprotective Peptides
GHK-Cu
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, a sequence first isolated from human plasma in the 1970s and later identified in saliva and urine. The free tripeptide binds copper with high affinity, and it is the copper-bound form that most of the published literature studies. Its plasma concentration in humans declines with age, which is part of why it has been examined in tissue remodelling and gene expression work. We supply it as a lyophilised powder at 50mg per vial, with a batch certificate of analysis reporting HPLC purity and mass spectrometry identity. The copper content is what gives the powder its characteristic blue colour, so a vial that looks white or off-white is not GHK-Cu.
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