GH Secretagogue Peptides
Ipamorelin
5mgC₃₈H₄₉N₉O₅
Key Research Findings
- Characterisation of the selective GHSR-1a-binding pentapeptide.
- Published receptor-selectivity studies versus cortisol-axis receptors.
- In-vitro pituitary cell-line assays on GH-secretion-pathway activity.
Overview
Ipamorelin is a synthetic pentapeptide ghrelin-receptor (GHSR-1a) agonist. Supplied as a lyophilised powder for in-vitro research use only.
Mechanism of Action
Reported in published in-vitro studies as a selective GHSR-1a ligand active on pituitary somatotroph cell-line assays. Not intended for human or veterinary use.
Research Effects
GHSR-1a Receptor Binding
Extensive ResearchReported in receptor-binding assays as a selective ligand of the ghrelin receptor (GHSR-1a).
Receptor-Selectivity Profile
Extensive ResearchPublished studies report minimal cross-reactivity with cortisol- and prolactin-axis receptor pathways.
Somatotroph Cell Assays
Moderate ResearchIn-vitro pituitary cell-line assays report effects on the GH-secretion pathway.
References
- [1]Venkova K, Mann W, Nelson R, et al.. Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus. J Pharmacol Exp Ther. 2009. PMID 19289567 · doi:10.1124/jpet.108.149211
Cited for the molecular pathways described above. Listing a study is not a claim about any outcome in humans.
Laboratory Research Only — All information on this page is provided for scientific research purposes only. This is a certified reference material sample sold and distributed for laboratory research only.
Quick Facts
Research Status Key
Featured in Bundles
Ipamorelin is included in the following Zenterex research peptide bundles.
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Tesamorelin
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