Copper & Collagen Peptides

IGF-1 LR3

C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉ (approximate)

Key Research Findings

Characterisation of the LR3-modified IGF-1 sequence and reduced IGFBP affinity.
Published cell-culture studies on PI3K/Akt-pathway activation.
In-vitro mitogenic assays in multiple cell lines.

£69.99

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Research Purposes Only · Not for human consumption

Overview

IGF-1 LR3 is a recombinant analogue of IGF-1, modified with an N-terminal extension and an Arg-for-Glu substitution at position 3. Supplied as a lyophilised powder for in-vitro research use only.

Mechanism of Action

Reported in published in-vitro studies as an IGF-1-receptor (IGF1R) ligand active on the PI3K/Akt and MAPK/ERK signalling cascades in cell-culture assays. Not intended for human or veterinary use.

Research Effects

IGF1R Binding

Extensive Research

Characterised in receptor-binding assays as a high-affinity ligand of the IGF-1 receptor.

PI3K/Akt Pathway Studies

Extensive Research

Published cell-culture studies report activation of the PI3K/Akt signalling cascade.

Mitogenic Cell Assays

Moderate Research

In-vitro assays report mitogenic activity in multiple cell lines used as research tools.

Research Purposes Only — All information on this page is provided for scientific research purposes only. This product is not intended for human consumption, diagnosis, treatment, or prevention of any disease.

Quick Facts

Molecular FormulaC₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉ (approximate)

Molecular Weight~9.11 kDa

CAS Number946870-92-4

Half-Life~20–30 hours (animal pharmacokinetic data)

SolubilityDilute acetic acid (0.1%)

Storage−20 °C

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