Research Purposes Only

IGF-1 LR3 1mg (IGF-1 LR3) lyophilised research peptide vial — UK lab-tested, for research use only

Copper & Collagen Peptides

IGF-1 LR3

1mg

C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉ (approximate)

Key Research Findings

  • Characterisation of the LR3-modified IGF-1 sequence and reduced IGFBP affinity.
  • Published cell-culture studies on PI3K/Akt-pathway activation.
  • In-vitro mitogenic assays in multiple cell lines.

Overview

IGF-1 LR3 is a recombinant analogue of IGF-1, modified with an N-terminal extension and an Arg-for-Glu substitution at position 3. Supplied as a lyophilised powder for in-vitro research use only.

Mechanism of Action

Reported in published in-vitro studies as an IGF-1-receptor (IGF1R) ligand active on the PI3K/Akt and MAPK/ERK signalling cascades in cell-culture assays. Not intended for human or veterinary use.

Research Effects

IGF1R Binding

Extensive Research

Characterised in receptor-binding assays as a high-affinity ligand of the IGF-1 receptor.

PI3K/Akt Pathway Studies

Extensive Research

Published cell-culture studies report activation of the PI3K/Akt signalling cascade.

Mitogenic Cell Assays

Moderate Research

In-vitro assays report mitogenic activity in multiple cell lines used as research tools.

Laboratory Research Only — All information on this page is provided for scientific research purposes only. This is a certified reference material sample sold and distributed for laboratory research only.

Quick Facts

Molecular FormulaC₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉ (approximate)
Molecular Weight~9.11 kDa
CAS Number946870-92-4
Half-Life~20–30 hours (animal pharmacokinetic data)
SolubilityDilute acetic acid (0.1%)
Storage−20 °C
More in Copper & Collagen Peptides

Research Status Key

Extensive Research
Moderate Research
Preliminary Research

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