KPV 10mg (KPV peptide) lyophilised research peptide vial — third-party lab-tested, for research use only

Cytoprotective Peptides

KPV

Name: KPV
Brand: Zenterex
SKU: 14
Price: 39.99 GBP
Availability: InStock

10mg

C₁₇H₃₂N₆O₆

Key Research Findings

Published cell-culture assays on epithelial NF-κB activation.
In-vitro antimicrobial activity reported in plate-assay studies.
Stability profile documented in lyophilised form at −20 °C.

£39.99

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Not sold for personal use

Zenterex does not supply these materials for human or animal administration, and does not use a “research only” label as cover for it. They are sold for laboratory work: assay, purity and degradation testing, reference standards and method development. Ordering confirms you are buying on that basis, and we expect every customer to hold to it.

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3+ units£35.9910% off
5+ units£33.9915% off

Certified reference material sample sold and distributed for Laboratory research only

Overview

KPV is a synthetic tripeptide fragment of the α-MSH C-terminal sequence. Supplied as a lyophilised powder for in-vitro research use only.

Mechanism of Action

Reported in published in-vitro and animal-model studies to interact with the MC1R melanocortin receptor and the NF-κB signalling pathway in epithelial cell-line assays. Not intended for human or veterinary use.

Research Effects

MC1R Receptor Binding

Extensive Research

Reported in receptor-binding assays as a ligand for the MC1R melanocortin receptor.

NF-κB Pathway Studies

Extensive Research

Cell-culture assays report effects on NF-κB-driven cytokine transcription in epithelial cell lines.

Antimicrobial Plate Assays

Moderate Research

Published in-vitro plate assays report activity against S. aureus, E. coli and Candida species.

References

[1]Kannengiesser K, Maaser C, Heidemann J, et al.. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease. Inflamm Bowel Dis. 2008. PMID 18092346 · doi:10.1002/ibd.20334
[2]Brzoska T, Bohm M, Lugering A, et al.. Terminal signal: anti-inflammatory effects of alpha-melanocyte-stimulating hormone related peptides beyond the pharmacophore. Adv Exp Med Biol. 2010. PMID 21222263 · doi:10.1007/978-1-4419-6354-3_8

Cited for the molecular pathways described above. Listing a study is not a claim about any outcome in humans.

Laboratory Research Only — All information on this page is provided for scientific research purposes only. This is a certified reference material sample sold and distributed for laboratory research only.

Quick Facts

Molecular FormulaC₁₇H₃₂N₆O₆

Molecular Weight416.47 g/mol

CAS Number62007-35-6

SequenceLys-Pro-Val

Half-Life~30 minutes (animal pharmacokinetic data)

SolubilityWater (1 mg/mL)

Storage−20 °C

Related Peptides

Cytoprotective Peptides

BPC-157

BPC-157 is a synthetic pentadecapeptide with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. It corresponds to a partial sequence of a larger protein described in human gastric juice, from which it takes the name Body Protection Compound. Unusually for a peptide of this length it is reported to be stable in gastric acid, which is why much of the published work administers it orally in animal models rather than by injection. We supply it as a lyophilised powder at 5mg per vial with an independent batch certificate of analysis. It is one of the more heavily published research peptides in the catalogue, with most of the literature coming from a single research group in Zagreb over roughly three decades.

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