Cytoprotective Peptides
TB-500
5mgC₂₁₂H₃₅₀N₅₆O₇₈S
Key Research Findings
- Goldstein et al. — characterisation of the Tβ4 sequence and actin-binding domain.
- Published cell-culture assays on keratinocyte and endothelial cell migration.
- Storage stability characterised in lyophilised form at −20 °C.
Overview
TB-500 is a synthetic analogue of the thymosin β4 (Tβ4) fragment. Supplied as a lyophilised powder for in-vitro research use only.
Mechanism of Action
Reported in published in-vitro and animal-model studies as a G-actin-sequestering peptide active on actin polymerisation and cell-migration assays. Not intended for human or veterinary use.
Research Effects
Actin Polymerisation
Extensive ResearchReported in cell-culture assays as a G-actin sequestering peptide affecting F-actin assembly.
Cell-Migration Assays
Moderate ResearchPublished in-vitro studies report effects on keratinocyte and endothelial cell migration.
Cytokine-Expression Studies
Moderate ResearchAnimal-model studies report changes in TNF-α and related cytokine expression under controlled conditions.
Laboratory Research Only — All information on this page is provided for scientific research purposes only. This is a certified reference material sample sold and distributed for laboratory research only.
Quick Facts
Research Status Key
Featured in Bundles
TB-500 is included in the following Zenterex research peptide bundles.
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