Cytoprotective Peptides
TB-500
C₂₁₂H₃₅₀N₅₆O₇₈S
Key Research Findings
- Goldstein et al. — characterisation of the Tβ4 sequence and actin-binding domain.
- Published cell-culture assays on keratinocyte and endothelial cell migration.
- Storage stability characterised in lyophilised form at −20 °C.
Overview
TB-500 is a synthetic analogue of the thymosin β4 (Tβ4) fragment. Supplied as a lyophilised powder for in-vitro research use only.
Mechanism of Action
Reported in published in-vitro and animal-model studies as a G-actin-sequestering peptide active on actin polymerisation and cell-migration assays. Not intended for human or veterinary use.
Research Effects
Actin Polymerisation
Extensive ResearchReported in cell-culture assays as a G-actin sequestering peptide affecting F-actin assembly.
Cell-Migration Assays
Moderate ResearchPublished in-vitro studies report effects on keratinocyte and endothelial cell migration.
Cytokine-Expression Studies
Moderate ResearchAnimal-model studies report changes in TNF-α and related cytokine expression under controlled conditions.
Research Purposes Only — All information on this page is provided for scientific research purposes only. This product is not intended for human consumption, diagnosis, treatment, or prevention of any disease.
Quick Facts
Research Status Key
Featured in Bundles
TB-500 is included in the following Zenterex research peptide bundles.
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