Repair / Recovery
BPC-157
C₆₂H₉₈N₁₆O₂₂
Key Research Findings
- Demonstrated consistent tendon-to-bone healing acceleration in multiple rodent models.
- Shown to protect the gastric mucosa and accelerate gut healing in inflammatory bowel disease models.
- Exhibits neuroprotective properties, with research suggesting benefits following traumatic brain injury.
- No reported toxicity or dose-limiting effects in animal studies to date.
Overview
BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It consists of 15 amino acids and has been studied extensively in animal models for its remarkable tissue-healing properties across multiple organ systems.
Mechanism of Action
BPC-157 is thought to upregulate growth hormone receptors and modulate nitric oxide (NO) synthesis, promoting angiogenesis and accelerating cell migration to sites of injury. It also appears to interact with the dopaminergic and serotonergic systems, contributing to its cytoprotective and neuroprotective effects.
Research Effects
Tissue Repair
Extensive ResearchMultiple controlled studies show accelerated healing of tendons, ligaments, muscles, and bones, attributed to upregulation of growth factor receptors and enhanced angiogenesis.
Gut Protection
Extensive ResearchResearch consistently demonstrates cytoprotective effects on gastric and intestinal mucosa, with studies showing benefit in models of NSAID-induced damage and inflammatory bowel disease.
Neuroprotection
Moderate ResearchAnimal models of brain and spinal cord injury suggest BPC-157 may reduce lesion size and improve functional recovery through dopaminergic modulation.
Anti-inflammatory
Moderate ResearchShown to reduce pro-inflammatory cytokine expression and modulate nitric oxide synthesis in several in vivo models.
Angiogenesis
Moderate ResearchPromotes formation of new blood vessels at injury sites, a key mechanism underlying its tissue repair properties.
Research Purposes Only — All information on this page is provided for scientific research purposes only. This product is not intended for human consumption, diagnosis, treatment, or prevention of any disease.
Quick Facts
Research Status Key
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