Cellular Peptides
MOTS-C
10mgC₁₀₀H₁₆₈N₃₀O₃₆
Key Research Findings
- Lee et al. — original characterisation of the mitochondria-encoded peptide and its nuclear translocation.
- Published cell-culture studies on AMPK activation under metabolic-stress conditions.
- Serum-analysis studies on age-related concentration decline.
Overview
MOTS-C is a synthetic 16-residue mitochondria-derived peptide encoded within the mitochondrial 12S rRNA gene. Supplied as a lyophilised powder for in-vitro research use only.
Mechanism of Action
Reported in published in-vitro and animal-model studies to activate AMPK (AMP-activated protein kinase) and to translocate to the nucleus under metabolic-stress assay conditions. Not intended for human or veterinary use.
Research Effects
AMPK Activation Assays
Moderate ResearchReported in cell-culture assays as an activator of AMP-activated protein kinase.
Nuclear-Translocation Studies
Moderate ResearchPublished in-vitro studies report nuclear translocation under metabolic-stress assay conditions.
Folate-Cycle Enzyme Studies
Preliminary ResearchEarly-stage cell-culture data on folate-cycle and one-carbon metabolism enzymes.
Laboratory Research Only — All information on this page is provided for scientific research purposes only. This is a certified reference material sample sold and distributed for laboratory research only.
Quick Facts
Research Status Key
Featured in Bundles
MOTS-C is included in the following Zenterex research peptide bundles.
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