Cellular Peptides
MOTS-C
C₁₀₀H₁₆₈N₃₀O₃₆
Key Research Findings
- Lee et al. — original characterisation of the mitochondria-encoded peptide and its nuclear translocation.
- Published cell-culture studies on AMPK activation under metabolic-stress conditions.
- Serum-analysis studies on age-related concentration decline.
Overview
MOTS-C is a synthetic 16-residue mitochondria-derived peptide encoded within the mitochondrial 12S rRNA gene. Supplied as a lyophilised powder for in-vitro research use only.
Mechanism of Action
Reported in published in-vitro and animal-model studies to activate AMPK (AMP-activated protein kinase) and to translocate to the nucleus under metabolic-stress assay conditions. Not intended for human or veterinary use.
Research Effects
AMPK Activation Assays
Moderate ResearchReported in cell-culture assays as an activator of AMP-activated protein kinase.
Nuclear-Translocation Studies
Moderate ResearchPublished in-vitro studies report nuclear translocation under metabolic-stress assay conditions.
Folate-Cycle Enzyme Studies
Preliminary ResearchEarly-stage cell-culture data on folate-cycle and one-carbon metabolism enzymes.
Research Purposes Only — All information on this page is provided for scientific research purposes only. This product is not intended for human consumption, diagnosis, treatment, or prevention of any disease.
Quick Facts
Research Status Key
Featured in Bundles
MOTS-C is included in the following Zenterex research peptide bundles.
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