Copper & Collagen Peptides
FOX04-DRI
C₁₀₆H₁₄₁N₂₁O₂₈S₂
Key Research Findings
- Baar et al. — characterisation of the FOXO4-binding D-retro-inverso peptide.
- Published cell-culture studies on p21 and p16 senescence-marker transcription.
- Animal-model in-vitro data on p53 nuclear-export pathway.
Overview
FOX04-DRI is a synthetic D-retro-inverso peptide designed to interfere with the FOXO4–p53 protein-protein interaction. Supplied as a lyophilised powder for in-vitro research use only.
Mechanism of Action
Reported in published in-vitro studies as a competitive binder of FOXO4 that releases nuclear-sequestered p53 in cell-culture senescence-model assays. Not intended for human or veterinary use.
Research Effects
FOXO4–p53 Interaction Assays
Moderate ResearchReported in cell-culture assays as a competitive disruptor of the FOXO4–p53 protein-protein interaction.
Senescence-Marker Studies
Moderate ResearchPublished in-vitro studies report changes in p21 and p16 transcription in cultured cells.
Apoptosis Cell-Culture Assays
Preliminary ResearchEarly-stage in-vitro apoptosis-marker studies in senescence cell models.
Research Purposes Only — All information on this page is provided for scientific research purposes only. This product is not intended for human consumption, diagnosis, treatment, or prevention of any disease.
Quick Facts
Research Status Key
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